Organic Chemistry

Hello, Readers.....I would like to explain the things in very short and easy way, especially this blog is for pharmacy students. i've prepared this notes in my college days and i hope it will help you to understand the different concepts in organic chemistry, Thank you and all the best.

Puvvu

Puvvu
Konvict

Saturday, September 5, 2020

Fries rearrangement Reaction

 Fries rearrangement Reaction



The phenol is first treated with acetic anhydride in the presence of aqueous sodium hydroxide to give phenyl acetate, The ester is then treated with aluminium chloride catalyst when the acyl group migrates from the phenolic oxygen to an ortho or para position of the ring. The product is a mixture of O And P-hydroxyacetophenone. 




The fries rearrangement reaction is also given by other phenols and introduces - COR group in the ortho or para position.






Puvvukonvict...........


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