Preparation method of DCC reagent and aluminium isoperoxide

 

DCC Reagent Preparation

1. Materials Needed:

• Dicyclohexylcarbodiimide (DCC): Commercially available as a white crystalline solid.
• Solvent (optional): Dry dichloromethane (DCM) or tetrahydrofuran (THF) can be used.

1. Procedure:

   • Step 1: If DCC is not already in a suitable solvent, dissolve it in an appropriate solvent like dichloromethane or THF.
   • Step 2: Stir the solution at room temperature to ensure complete dissolution.
   • Step 3: Filter the solution if necessary to remove any insoluble impurities.
   • Step 4: Store the DCC solution in a well-sealed container, away from moisture and light, to prevent hydrolysis.

Aluminum Isopropoxide Preparation

1. Materials Needed:

• Aluminum Metal: Clean, dry aluminum foil or powder.
• Isopropanol (Isopropyl Alcohol): A common alcohol solvent.
• Anhydrous conditions: Dry atmosphere to prevent moisture interference.

1. Procedure:

   • Step 1: In a dry, inert atmosphere (such as under nitrogen), place aluminum metal in a reaction vessel.
   • Step 2: Slowly add isopropanol to the aluminum. The reaction between aluminum and isopropanol produces aluminum isopropoxide and hydrogen gas.
   • Step 3: Stir the mixture until the reaction is complete, which may take some time.
   • Step 4: Once the reaction has stopped, filter out any residual aluminum or other impurities.
   • Step 5: The resulting aluminum isopropoxide can be purified if necessary and stored in a sealed container under an inert atmosphere to prevent hydrolysis.

Always use appropriate safety measures when handling these chemicals, including personal protective equipment and working in a well-ventilated area or fume hood.